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CBD oil for boosting endorphins

Many use opioid painkillers, whether it’s for a short time to deal with a broken bone, or for months or even years to deal with chronic pain. Because opioids such as oxycodone or fentanyl are highly addictive and carry a real risk of overdose, doctors are reluctant to prescribe them, and encourage patients to use other methods of pain management. One side effect of taking opioids is that your body makes less of your natural opioids, called endorphins, because the medications hyperactivate opioid receptors. When you stop taking opioids, it can take weeks or even months for your body to return to producing normal levels of endorphins, resulting in physical achiness and depression.

One of the ways to recover more comfortably from stopping the use of opioid medication is to boost endorphin production. Meditation, acupuncture, massage, hot baths, and any type of exercise lasting longer than 30 minutes can all raise endorphin levels, helping you feel relaxed and pain-free. It’s no wonder why these lifestyle treatments are suggested by professionals for people recovering from opioid abuse.


When marijuana enters the body, it interacts with the endocannabinoid system, or ECS, which serves as a regulatory framework.

The ECS is made up of two types of receptors; CB1 and CB2 respectively. You can find these receptors throughout the entire body. They work alongside body-made chemicals to regulate many critical physiological processes, including but not limited to hunger, memory, wakefulness, seizure reduction, and pain sensation. 

These chemicals, called endocannabinoids, interact with the CB1 and CB2 receptors. Two of these endocannabinoids, anandamide and 2-Arachidonoylglycerol (2-AG for short), bind and block ECS receptors. They work in sequence as regulators for bodily processes.  

In terms of chronic pain, the ECS releases anandamide, producing feel-good effects similar to that of an endorphin. After a certain amount of time, fatty acid amide hydrolase, or FAAH, gets released into the synapse. 

"Cannabinoid receptor agonists as well as inhibitors of endocannabinoid-regulating enzymes fatty acid amide hydrolase and monoacylglycerol lipase produce reliable antinociceptive effects, and offer opioid-sparing antinociceptive effects.” - Donvito et al, 2018.

Ergo, cannabinoids derived from cannabis can help mask nociception, the process by which the body signals pain sensation to the brain. By acting as an antinociceptive, cannabis removes physical awareness of the painful stimulus without the need for harmful opioids. 

Taking CBD oil can therefore aid in the natural release of endorphins. The cannabinoids and terpenes in CBD oil not only help relax you, but they also enhance the release of endorphins in the brain.


How to use:

CBD oil works best to boost endorphin levels if you take it internally every day after stopping opioid use. Take 10–25 milligrams of CBD oil under the tongue and held for 30 seconds each morning for up to three months to rebalance your opioid receptors and feel your best.


Source: CBD Oil for Health - Michele Ross,

https://gardenculturemagazine.com/cannabis-and-chronic-pain-the-endorphin-connection